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Search Results for " transforming growth factor, beta 1 "
Targets Recommended: ALK Autophagy TGF-beta/Smad

17

抑制剂 & 化合物

2

天然产物

1759

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1942 DMH-1

DMH1

ALK; Autophagy; TGF-beta/Smad Angiogenesis; Autophagy; Stem Cells; Tyrosine Kinase/Adaptors
DMH-1 是一种选择性 BMP 抑制剂,对 ALK1、ALK2、ALK3和 ALK6的 IC50值分别为 27、107.9、<5和 47.6 nM。
T16708 R-268712

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
R-268712 是选择性的 ALK5 抑制剂(IC50:2.5 nM)。
T4283 SRI-011381

TGF-beta/Smad Stem Cells
SRI011381 是口服具有活力的 TGF-β信号通路的激活剂,具有神经保护活性。
T23127 PD-161570

PD 161570

EGFR; FGFR; PDGFR; Src Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD-161570 是一种有效的 ATP 竞争性人 FGF-1 受体抑制剂,IC50 为 39.9 nM,Ki 为 42 nM。它还是骨形态发生蛋白 (BMPs) 和TGF-β信号抑制剂。它抑制PDGF 刺激的自磷酸化和FGF-1受体磷酸化,IC50分别为 450 和 622 nM。它抑制 PDGFR、EGFR 和 c-Src 酪氨酸激酶,IC50 值分别为 310、240 和 44 nM。
T2273 ITD-1

4-[1,1'-联苯]-4-基-1,4,5,6,7,8-六氢-2,7,7-三甲基-5-氧代-3-喹啉羧酸乙酯

TGF-beta/Smad Stem Cells
ITD1 是一个选择性的TGFβ受体抑制剂(IC50:460 nM)。
T5129 SRI-011381 hydrochloride

SRI-011381 hydrochloride [1629138-41-5(free base)]

TGF-beta/Smad Stem Cells
SRI-011381 hydrochloride 是口服具有活力的TGF-β信号通路的激活剂,具有神经保护活性。
T9010 IMM-H007

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
IMM-H007 是一种新型降脂剂,可增加 abca1 蛋白的表达。
T6146 Dorsomorphin dihydrochloride

BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

AMPK; Autophagy; TGF-beta/Smad Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种选择性和 ATP 竞争性的AMPK 抑制剂,Ki 为 109 nM。它诱导自噬,通过靶向抑制 I 型受体ALK2,ALK3和ALK6来抑制 BMP 途径。
T11052L Disitertide acetate

P144 acetate,Disitertide acetate(272105-42-7 Free base)

TGF-beta/Smad Stem Cells
Disitertide acetate (P144 acetate) 是转化生长因子 TGFβ1 的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide acetate 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T6496 Vactosertib

TEW-7197,EW-7197

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
Vactosertib (EW-7197) 是有效的、具有 ATP 竞争性的、具有口服活性的激活素受体样激酶 5 (ALK5) 抑制剂(IC50:12.9 nM)。它还以纳摩尔浓度抑制 ALK2 和 ALK4 (IC50为 17.3 nM),表现出强大的抗转移活性和抗癌作用。
T25700 Levormeloxifene

Levormeloxifene is a selective modulator of the estrogen receptor. It inhibits the production of vaginal tropoelastin and transforming growth factor-beta 1.
T80272 Vicatertide

SB-01

Vicatertide为TGF beta-1抑制剂。
T79543 J27644

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
J27644为一高效HDAC抑制剂,能缓解TGF-β所引发的肺纤维化现象。
T75716 Disitertide TFA

Disitertide (P144) TFA 是转化生长因子TGFβ1的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide TFA 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T75717 Disitertide diammonium

Disitertide (P144) diammonium 是转化生长因子TGFβ1的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide diammonium 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T79603 3,7-DMF

TGF-beta/Smad Stem Cells
3,7-DMF作为一种口服活性抑制剂,有效抑制了TGF-β1诱导的HSC活化,并通过诱导抗氧化基因及淬灭ROS为研究肝纤维化提供了潜在应用。
T35438 (5E)-7-Oxozeaenol

(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 μM, respectively.2 |1. Fakhouri, L., El-Elimat, T., Hurst, D.P., et al. Isolation, semisynthesis, covalent docking and transforming growt...

化合物

DMH-1
Cat.No: T1942
Synonym: DMH1
Target: ALK, Autophagy, TGF-beta/Smad
R-268712
Cat.No: T16708
Synonym:
Target: ALK, TGF-beta/Smad
SRI-011381
Cat.No: T4283
Synonym:
Target: TGF-beta/Smad
PD-161570
Cat.No: T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
ITD-1
Cat.No: T2273
Synonym: 4-[1,1'-联苯]-4-基-1,4,5,6,7,8-六氢-2,7,7-三甲基-5-氧代-3-喹啉羧酸乙酯
Target: TGF-beta/Smad
SRI-011381 hydrochloride
Cat.No: T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
IMM-H007
Cat.No: T9010
Synonym:
Target: Others, AMPK
Dorsomorphin dihydrochloride
Cat.No: T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
Disitertide acetate
Cat.No: T11052L
Synonym: P144 acetate,Disitertide acetate(272105-42-7 Free base)
Target: TGF-beta/Smad
Vactosertib
Cat.No: T6496
Synonym: TEW-7197,EW-7197
Target: ALK, TGF-beta/Smad
Levormeloxifene
Cat.No: T25700
Synonym:
Target:
Vicatertide
Cat.No: T80272
Synonym: SB-01
Target:
J27644
Cat.No: T79543
Synonym:
Target: HDAC
Disitertide TFA
Cat.No: T75716
Synonym:
Target:
Disitertide diammonium
Cat.No: T75717
Synonym:
Target:
3,7-DMF
Cat.No: T79603
Synonym:
Target: TGF-beta/Smad
(5E)-7-Oxozeaenol
Cat.No: T35438
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6856 Halofuginone

卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
Halofuginone (RU-19110) 是Febrifugine 的衍生物,是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂,可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
T3524 Halofuginone hydrobromide

卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
Halofuginone hydrobromid 是Febrifugine 的衍生物,是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂,并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。

天然产物

Halofuginone
Cat.No: T6856
Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Halofuginone hydrobromide
Cat.No: T3524
Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Cat. No. Product Name Species Expression System
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

transforming growth factor, b...

Human,Rhesus,Cynomolgus,Canine CHO Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant

transforming growth factor, b...

Mouse,Rat HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

transforming growth factor, β...

Cynomolgus HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His)

TGF β1,transforming growth fa...

Rat HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His)

CED,DPD1,transforming growth ...

Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TGF-Beta-1,TGFB1,Transforming...

Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His)

transforming growth factor, b...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-06247 TGF beta 3 Protein, Human, Recombinant (hFc)

TGF-beta 3,ARVD,TGF β3,TGF-β3,TGF-beta3,

Human HEK293 Cells
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1.
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant

Glioblastoma-derived T-cell suppressor factor,TGF-β...

Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant

transforming growth factor β-2,BS...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPY-01009 TGFBI Protein, Human, Recombinant (His)

CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transfor...

Human HEK293 Cells
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His)

transforming growth factor, β...

Canine HEK293 Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated

transforming growth factor, b...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated

TGFB,TGF β1,转化生长因子,TGF-beta 1,

Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Transforming growth factor β-...

Mouse HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)

转化生长因子,Transforming growth factor...

Cynomolgus HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated

transforming growth factor β1...

Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant

TGFB,TGFbeta,CEDLAP,TGF-beta-1,TG...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc)

AAT5,SKR4,TGFR-1,LDS1,transforming

Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1.
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc)

tβR-I,ALK5,AAT5,TGFR-1,LDS2A,LDS1,tran...

Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36897-1.
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)

LDS1,ALK-5,LDS2A,AAT5,SKR4,transforming

Human Baculovirus Insect Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62.6 kDa and the accession number is P36897-1.
TMPJ-01129 SMAD1 Protein, Human, Recombinant (GST)

hSMAD1,Transforming Growth Fa...

Human E. coli
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcriptional modulator SMAD 1 is activated by bone morphogenetic proteins type 1 receptor kinase. Defects in SMAD1 may cause primary pulmonary hypertension (PPH1), characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated ...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)

tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant

Latency-associated peptide,TGF-beta-3,Transform...

Human,Mouse,Rat HEK293 Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regu...
TMPK-00259 Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TGF-beta3,TGFβ,TGF-β,TGF-β3,TGFB3,ARVD,TGFβ3,转化生长因子...

Human HEK293 Cells
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi...
TMPK-00258 Latent TGF beta 3 Protein, Human, Recombinant (His)

TGFβ3,转化生长因子,TGF-β3,TGF-beta3,TGFβ,TGF-β,ARVD,TGFB3...

Human HEK293 Cells
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 45.9 kDa and t...
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi)

TAAD2,LDS2B,LDS2,MFS2,TGFBR2,AAT3,LDS1B,TGFβR2,T

Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The pred...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated

TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated

LDS2B,TbetaR-II,TGFβR2,LDS2,RIIC,TGF-β RII/TGFBR2,T...

Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi...
TMPH-01699 SMAD2 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3...
TMPH-03206 ITGB8 Protein, Rabbit, Recombinant (His & Myc)

Rabbit E. coli
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis. ITGB8 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli ...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His)

Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 acti...
TMPY-04468 STK16 Protein, Human, Recombinant (His & NusA)

MPSK,serine/threonine kinase 16,TSF1,KRCT,...

Human E. coli
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c...
TMPY-04899 OGN/Osteoglycin Protein, Human, Recombinant (His)

OIF,OG,osteoglycin,SLRR3A

Human HEK293 Cells
OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epith...
TMPJ-00271 SMAD3 Protein, Human, Recombinant (His & Flag)

SMAD 3,Mothers against DPP homolog 3,hMAD-3,MADH3,JV1

Human E. coli
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so doing transduce the signal into the nucleus. Receptor-regulated SMAD is an intracellular signal transducer and transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. SMAD3 binds the TRE element in the promoter region of many genes that are regulated...
TMPJ-00361 Endoglin Protein, Human, Recombinant (Trx & His)

CD105,END,Endoglin,ENG

Human E. coli
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins an...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD2

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor rec...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
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重组蛋白

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
Cat.No: TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant
Cat.No: TMPY-00608
Species: Mouse,Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04211
Species: Cynomolgus
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03945
Species: Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01133
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPJ-00249
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00500
Species: Mouse
Expression System: HEK293 Cells
TGF beta 3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06247
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant
Cat.No: TMPJ-00258
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
TGFBI Protein, Human, Recombinant (His)
Cat.No: TMPY-01009
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-00229
Species: Canine
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05313
Species: Mouse
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05521
Species: Human
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00772
Species: Mouse
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00622
Species: Cynomolgus
Expression System: HEK293 Cells
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00250
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00771
Species: Mouse,Rat
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05771
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-01358
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
Cat.No: TMPY-04366
Species: Human
Expression System: Baculovirus Insect Cells
SMAD1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01129
Species: Human
Expression System: E. coli
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00305
Species: Human
Expression System: HEK293 Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
Cat.No: TMPJ-00254
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00259
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 3 Protein, Human, Recombinant (His)
Cat.No: TMPK-00258
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00328
Species: Human
Expression System: HEK293 Cells
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Cat.No: TMPK-00306
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Cat.No: TMPK-00329
Species: Human
Expression System: HEK293 Cells
SMAD2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01699
Species: Human
Expression System: E. coli
ITGB8 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03206
Species: Rabbit
Expression System: E. coli
NRROS Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02803
Species: Mouse
Expression System: E. coli
STK16 Protein, Human, Recombinant (His & NusA)
Cat.No: TMPY-04468
Species: Human
Expression System: E. coli
OGN/Osteoglycin Protein, Human, Recombinant (His)
Cat.No: TMPY-04899
Species: Human
Expression System: HEK293 Cells
SMAD3 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00271
Species: Human
Expression System: E. coli
Endoglin Protein, Human, Recombinant (Trx & His)
Cat.No: TMPJ-00361
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
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